The most successful programs in men's Division I college basketball history -- ranked by winning percentage, with a minimum of 25 seasons in competition at the Division I level -- through the 2007-08 season:
Best Winning Percentage in Division I
| Team | Wins | Losses | Winning Percentage |
| Kentucky | 1966 | 621 | .760 |
| North Carolina | 1950 | 699 | .736 |
| UNLV | 1037 | 418 | .713 |
| Kansas | 1943 | 785 | .712 |
| UCLA | 1646 | 717 | .697 |
| Duke | 1846 | 808 | .696 |
| Syracuse | 1725 | 796 | .684 |
| Western Kentucky | 1577 | 771 | .672 |
| St. John's | 1670 | 850 | .663 |
| Utah | 1613 | 848 | .655 |
| Louisville | 1556 | 825 | .654 |
| Illinois | 1585 | 843 | .653 |
| Indiana | 1635 | 884 | .649 |
| Arizona | 1547 | 844 | .647 |
| Missouri State | 1487 | 813 | .647 |
| Notre Dame | 1630 | 893 | .646 |
| Arkansas | 1473 | 806 | .646 |
| Temple | 1689 | 948 | .641 |
| Penn | 1647 | 931 | .639 |
| Connecticut | 1468 | 834 | .638 |